Interoception
Interoception
Zhao, Q. (2024). Navigating internal senses: A road map for the vagal interoceptive system. Science Aug 2;385(6708):507-508 (Essay).
Zhao, Q., Yu, C.D., Wang, R., Xu, Q.J., Dai Pra, R., Zhang, L., and Chang, R.B. (2022). A multidimensional coding architecture of the vagal interoceptive system. Nature 603, 878-884.
Li, Z., Zhang, X., Zhu, W., Xu, Q., Yu, C., Zhao, Q., Siebe, S., Zhang, C., Costa Lima, B.G., Li, X., Winger, K.I., Nasiri, A.R., Caplan, M.J., Chang, R.B., Wang, A., Belfort de Aguiar, R., Hwang, J.J., Perry, R.J. (2023). GDF15 is a Critical Renostat in the Defense Against Hypoglycemia. bioRxiv. doi: https://doi.org/10.1101/2023.06.22.546095
Piezo1 (resolved 78 TMs)
Piezo2 (all 114 TMs)
Mechanosensation (* equal contribution)
Wang, L.*, Zhou, H.*, Zhang, M.*, Liu, W.*, Deng, T., Zhao, Q., Li, Y., Lei, J., Li, X., and Xiao, B. (2019). Structure and mechanogating of the mammalian tactile channel PIEZO2. Nature 573, 225-229.
· Previewed in Nature ‘News and Views’. Edwin W. McCleskey (2019). A mechanism for touch. Nature 573, 199-200.
Zhao, Q.*, Zhou, H.*, Chi, S.*, Wang, Y.*, Wang, J., Geng, J., Wu, K., Liu, W., Zhang, T., Dong, M.Q., Wang, J., Li, X., Xiao, B.(2018). Structure and mechanogating mechanism of the Piezo1 channel. Nature 554, 487-492.
· Previewed in Nature ‘News and Views’. Yuh Nung Jan & Lily Yeh Jan (2018). Force-activated ion channels in close-up. Nature 554, 469-470.
Wang, Y.*, Chi, S.*, Guo, H., Li, G., Wang, L., Zhao, Q., Rao, Y., Zu, L., He, W., and Xiao, B. (2018). A lever-like transduction pathway for long-distance chemical- and mechano-gating of the mechanosensitive Piezo1 channel. Nat Commun 9, 1300.
Zhang, T.*, Chi, S.*, Jiang, F., Zhao, Q., and Xiao, B. (2017). A protein interaction mechanism for suppressing the mechanosensitive Piezo channels. Nat Commun 8, 1797.
Zhao, Q.*, Wu, K.*, Geng, J.*, Chi, S.*, Wang, Y., Zhi, P., Zhang, M., and Xiao, B. (2016). Ion permeation and mechanotransduction mechanisms of mechanosensitive Piezo channels. Neuron 89, 1248-1263.
· Previewed in Neuron ‘Preview’. Nurunisa Akyuz, Jeffrey R. Holt (2016). Plug-N-Play: Mechanotransduction Goes Modular. Neuron. 2016 Mar 16;89(6):1128-1130.
Ge, J.*, Li, W.*, Zhao, Q.*, Li, N.*, Chen, M., Zhi, P., Li, R., Gao, N., Xiao, B., and Yang, M. (2015). Architecture of the mammalian mechanosensitive Piezo1 channel. Nature 527, 64-69.
Reviews (* equal contribution)
Zhao, Q.*, Zhou, H.*, Li, X., and Xiao, B. (2019). The mechanosensitive Piezo1 channel: a three-bladed propeller-like structure and a lever-like mechanogating mechanism. FEBS J 286, 2461-2470.
Geng, J.*, Zhao, Q.*, Zhang, T.*, and Xiao, B. (2017). In touch with the mechanosensitive Piezo channels: structure, ion permeation, and mechanotransduction. Curr Top Membr 79, 159-195.